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Clinical trials for Blunt Trauma

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43865   clinical trials with a EudraCT protocol, of which   7286   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    19 result(s) found for: Blunt Trauma. Displaying page 1 of 1.
    EudraCT Number: 2005-002059-41 Sponsor Protocol Number: F7Trauma-1711 Start Date*: 2005-07-07
    Sponsor Name:Novo Nordisk A/S
    Full Title: A multi-center, randomized, double-blind, parallel group, placebo controlled trial to evaluate the efficacy and safety of activated recombinant factor VII (rFVIIa/NovoSeven®/NiaStase®) in severely ...
    Medical condition: Traumatic Hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    8.0 10053476 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) BE (Completed) GB (Completed) ES (Completed) CZ (Completed) IT (Completed) FI (Completed) SE (Completed) PT (Prematurely Ended) SI (Completed) GR (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-000660-89 Sponsor Protocol Number: 999 Start Date*: 2006-03-23
    Sponsor Name:Timo Iirola
    Full Title: The effect of dexmedetomidine sedation on intracranial and cerebral perfusion pressures in patients with acute severe brain injury
    Medical condition: Acute blunt traumatic brain injury with intracranial abnormalities on the initial computed tomography (CT) scan consistent with head trauma, initial Glasgow Coma Scale (GCS) score ≤8 or GCS score d...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003778-30 Sponsor Protocol Number: DRO-200/III/21/1 Start Date*: 2021-12-29
    Sponsor Name:Drossapharm AG
    Full Title: Randomized, controlled, multi-center trial to evaluate the efficacy and safety of Lixim 70 mg wirkstoffhaltiges Pflaster (etofenamate 70 mg medicated plaster) vs. placebo in the local symptomatic a...
    Medical condition: Acute strains, sprains or bruises of soft tissues following blunt trauma, e.g. sports injuries
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-005217-41 Sponsor Protocol Number: 51-03FPAEU Start Date*: 2021-09-06
    Sponsor Name:Lead Chemical Company Ltd
    Full Title: Randomized, controlled, multi-center trial to evaluate the efficacy and safety of a Flurbiprofen 40 mg cutaneous hydrogel medicated plaster vs. placebo and vs. a marketed active comparator in the l...
    Medical condition: pain in acute strains, sprains or bruises of the soft tissues following blunt trauma, e.g. sports injuries
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002255-10 Sponsor Protocol Number: IRMINEpilot Start Date*: 2016-06-30
    Sponsor Name:Abertawe Bro Morgannwg University Health Board
    Full Title: INFLAMMATORY RESPONSE IN MAJOR INJURY & RECOMBINANT HUMAN ERYTHROPOIETIN (IRMINE) - A PILOT STUDY
    Medical condition: Post-trauma multiple organ failure: a manifestation of the systemic inflammatory/immune response to major injuries.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004870 10021459 Immunodeficiency secondary to trauma LLT
    20.0 100000004867 10028237 Multiple organ failure LLT
    20.0 10022117 - Injury, poisoning and procedural complications 10044461 Trauma LLT
    20.0 10022117 - Injury, poisoning and procedural complications 10044541 Traumatic shock PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001038-32 Sponsor Protocol Number: 48-03LXPU Start Date*: 2019-10-15
    Sponsor Name:Lead Chemical Company Ltd
    Full Title: Randomized, controlled, double-blind, multi-center trial to evaluate the efficacy and safety of a Loxoprofen sodium 60 mg tape medicated plaster vs. placebo in the local symptomatic and short-term ...
    Medical condition: Acute blunt, soft tissue injuries of the limbs
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10041775 Sprains and strains of ankle and foot LLT
    20.0 100000004863 10032894 Other specified sites of sprains and strains LLT
    20.0 100000004863 10041777 Sprains and strains of elbow and forearm LLT
    20.0 100000004863 10041790 Sprains and strains of shoulder and upper arm LLT
    20.0 100000004863 10041798 Sprains and strains of wrist and hand LLT
    21.0 100000004866 10019428 Hematoma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-003543-29 Sponsor Protocol Number: 48-04LXPU Start Date*: 2021-05-07
    Sponsor Name:Lead Chemical Company Ltd.
    Full Title: Randomized, controlled, multi-center trial to evaluate the efficacy and safety of a Loxoprofen sodium 60 mg medicated plaster vs. placebo and vs. a marketed comparator in the local symptomatic and ...
    Medical condition: Acute blunt, soft tissue injuries of the muscles or limbs
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002168-84 Sponsor Protocol Number: 839 Start Date*: 2008-01-07
    Sponsor Name:Kneipp-Werke
    Full Title: Wirksamkeit und Verträglichkeit von Kneipp Arnika Salbe S bei stumpfen Sportverletzungen im Vergleich zu Ibutop Creme (Efficacy and Safety of Kneipp Arnika Salbe S for blunt impact sport injuries c...
    Medical condition: Patients with blunt impact injuries (traumatic injuries)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10044528 Traumatic injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013115-35 Sponsor Protocol Number: MP4OX-09-TRA-204 Start Date*: 2009-11-05
    Sponsor Name:Sangart, Inc.
    Full Title: A multi-center, randomized, double-blind, controlled dose-finding study to evaluate the safety and efficacy of MP4OX treatment plus standard of care in severely injured trauma patients with lactic ...
    Medical condition: Trauma with lactic acidosis due to hemorrhagic shock
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023676 Lactic acidosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023129-39 Sponsor Protocol Number: MP4OX-10-TRA-205 Start Date*: 2011-03-22
    Sponsor Name:Sangart, Inc.
    Full Title: Estudio multicéntrico, aleatorizado, en doble ciego y controlado, para evaluar la seguridad y la eficacia del tratamiento con MP4OX, añadido al tratamiento habitual, en pacientes con traumatismo se...
    Medical condition: Pacientes con traumatismo severo y acidosis láctica por shock hemorrágico.//Severely injured trauma patients with lactic acidosis due to hemorrhagic shock.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10050841 Hemorrhagic shock LLT
    12.1 10023676 Lactic acidosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) AT (Completed) DE (Completed) GB (Completed) NO (Ongoing) IT (Ongoing) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001589-17 Sponsor Protocol Number: KN 38-7271-001 Start Date*: Information not available in EudraCT
    Sponsor Name:KeyNeurotek Pharmaceuticals AG
    Full Title: A doubel-blind, parallel-group, Phase IIa study to investigate the efficacy, safety and pharmacokinetics of two dose levels of KN 38-7271 versus placebo in comatose patients with severe traumatic b...
    Medical condition: Comatose patients with traumatic brain injury (TBI).
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000556-19 Sponsor Protocol Number: 6011 Start Date*: 2021-10-20
    Sponsor Name:Rigshospitalet, Department of Anaesthesia, Centre of Head and Orthopaedics
    Full Title: Comparing Restrictive vs. Liberal Oxygen Strategies for Trauma Patients: The TRAUMOX2 Trial
    Medical condition: Victims of trauma are often healthy individuals prior to the incident, but acquire numerous complications including sepsis and pulmonary complications and diminished quality of life after trauma. W...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10033316 Oxygen saturation PT
    20.0 100000004865 10050322 Oxygen supplementation LLT
    20.0 10022891 - Investigations 10033323 Oxygen tension LLT
    20.0 10022891 - Investigations 10033324 Oxygen tension abnormal NOS LLT
    20.0 10022891 - Investigations 10033325 Oxygen tension decreased LLT
    20.0 10022891 - Investigations 10033326 Oxygen tension increased LLT
    20.0 10022891 - Investigations 10033327 Oxygen tension normal LLT
    20.1 10022891 - Investigations 10068430 Arterial oxygen saturation LLT
    20.1 10022891 - Investigations 10068431 Arterial oxygen saturation increased LLT
    20.1 10022891 - Investigations 10068432 Arterial oxygen saturation decreased LLT
    20.1 10022891 - Investigations 10068433 Arterial oxygen saturation abnormal LLT
    20.1 10022891 - Investigations 10068434 Arterial oxygen partial pressure increased LLT
    20.1 10022891 - Investigations 10068435 Arterial oxygen partial pressure decreased LLT
    20.1 10022891 - Investigations 10068436 Arterial oxygen partial pressure abnormal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002176-27 Sponsor Protocol Number: HC-G-H-1505 Start Date*: 2017-08-30
    Sponsor Name:Fresenius Kabi Deutschland GmbH
    Full Title: Pragmatic, prospective, randomized, controlled, double-blind, multicentre, multinational study on the safety and efficacy of a 6% Hydroxyethyl starch (HES) solution versus an electrolyte solution ...
    Medical condition: Hypovolaemia due to acute blood loss in trauma surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10021137 Hypovolaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) CZ (Completed) NL (Completed) ES (Restarted) FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2020-005165-14 Sponsor Protocol Number: TK-254R-0201 Start Date*: 2021-03-25
    Sponsor Name:Teikoku Seiyaku Co Ltd.
    Full Title: Randomized, controlled, double-blind, multi-center trial to evaluate the
    Medical condition: Acute strains, sprains or bruises of the extremities following blunt trauma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10002549 Ankle sprain LLT
    20.0 100000004863 10002550 Ankle sprains and strains LLT
    20.0 100000004863 10028338 Muscle sprains LLT
    20.0 100000004859 10028361 Muscular pain LLT
    21.1 100000004859 10028362 Muscular pains LLT
    20.1 100000004863 10006502 Bruise LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-004343-92 Sponsor Protocol Number: 21559 Start Date*: 2021-06-23
    Sponsor Name:Bayer Healthcare LLC.
    Full Title: Randomized, Controlled, Double-blind, Placebo-controlled, Multi-center Hypothesis-finding Trial to Compare the Efficacy and Safety of a 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel and ...
    Medical condition: acute strains, sprains or bruises of the lower extremities following blunt trauma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001401-13 Sponsor Protocol Number: RRK5174 Start Date*: 2016-04-07
    Sponsor Name:University Hospitals Birmingham NHS Foundation Trust
    Full Title: A Multi-Centre Randomised Controlled Trial of Pre-Hospital Blood Product Administration versus Standard Care for Traumatic Haemorrhage
    Medical condition: Hypotension after trauma, due to haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022117 - Injury, poisoning and procedural complications 10053476 Traumatic haemorrhage PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-004974-16 Sponsor Protocol Number: IL1ra03 Start Date*: 2018-11-08
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMISED CLINICAL DOSE-RANGING STUDY TREATING MODERATE-SEVERE TRAUMATIC BRAIN INJURY PATIENTS WITH RECOMBINANT HUMAN INTERLEUKIN 1 RECEPTOR ANTAGONIST.
    Medical condition: We wish to study the drug Kineret in patients suffering from moderate-to-severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    20.1 10029205 - Nervous system disorders 10051288 Central nervous system inflammation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004480-12 Sponsor Protocol Number: 2017-991 Start Date*: 2018-01-16
    Sponsor Name:Rigshospitalet
    Full Title: Restrictive vs. Liberal Oxygen Therapy for Trauma patients. PILOT: The TRAUMOX Trial
    Medical condition: Victims of trauma are often healthy individuals prior to the incident, but acquire numerous complications including sepsis and pulmonary complications as well as long-term complications and dimini...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10050322 Oxygen supplementation LLT
    20.0 100000004848 10033321 Oxygen saturation low LLT
    20.0 100000004848 10033323 Oxygen tension LLT
    20.0 100000004848 10033324 Oxygen tension abnormal NOS LLT
    20.0 100000004848 10033325 Oxygen tension decreased LLT
    20.0 100000004848 10033326 Oxygen tension increased LLT
    20.0 100000004848 10033327 Oxygen tension normal LLT
    20.0 100000004848 10033319 Oxygen saturation high LLT
    20.0 100000004848 10059945 Partial arterial pressure of oxygen LLT
    20.1 100000004848 10068430 Arterial oxygen saturation LLT
    20.1 100000004848 10068431 Arterial oxygen saturation increased LLT
    20.1 100000004848 10068432 Arterial oxygen saturation decreased LLT
    20.1 100000004848 10068433 Arterial oxygen saturation abnormal LLT
    20.1 100000004848 10068434 Arterial oxygen partial pressure increased LLT
    20.1 100000004848 10068435 Arterial oxygen partial pressure decreased LLT
    20.1 100000004848 10068436 Arterial oxygen partial pressure abnormal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-002862-11 Sponsor Protocol Number: CXA-NP-11-04 Start Date*: 2015-07-27
    Sponsor Name:Cubist Pharmaceuticals GmbH
    Full Title: A Prospective, Randomized, Double-Blind, Multicenter, Phase 3 Study to Assess the Safety and Efficacy of Intravenous Ceftolozane/tazobactam Compared With Meropenem in Adult Patients with Ventilated...
    Medical condition: Ventilated Nosocomial Pneumonia
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10052596 Nosocomial pneumonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) EE (Completed) DE (Completed) BE (Completed) LV (Completed) CZ (Completed) HU (Completed) SK (Completed) AT (Completed) GR (Completed) PT (Completed) HR (Completed) IT (Completed)
    Trial results: View results
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